Curriculum

• Corso online: “Benessere animale: riproducibilità, nuovi marcatori. Digital Ventilated Cages (DVC^®): visione tecnologica ed applicazioni”. Webinar, 20 e 23 Settembre 2021
• Convegno “Il Microbiota nella Regolazione Redox dei processi infiammatori: prospettive diagnostiche e terapeutiche nelle Sindromi da Sensibilizzazione Centrale”. Messina, 2 Ottobre 2020
• Corso per tecnici addetti allo stabulario: protezione degli animali utilizzati ai fini scientifici. Caltanissetta, 16-18 Maggio 2018
• XII Sphingolipid Club Meeting and SLC Advanced course. Trabia, 6-10 Settembre 2017
• Corso di aggiornamento su “DNA sequencing from Sanger to Next Generation”. Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali. Messina, 13 Aprile 2016 
• Corso di aggiornamento su “A matrix of life and death: a dialogue on the extracellular matrix”. Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali. Messina, 13 Aprile 2016
• Corso di aggiornamento su “The interactome of Transglutaminase 2 in Chronic Kindney Disease (CDK)”.  Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali. Messina, 13 Aprile 2016 
• Corso di aggiornamento su “Medicina di laboratorio: approccio multidisciplinare e strategie vincenti”. S.I.Bio.C, Sant’Agata di Militello, 26 Settembre 2014
• Corso di aggiornamento su "La Spettrometria di Massa al Servizio della Salute Pubblica". Dipartimento di Scienze Biomediche, Odontoiatriche e delle Immagini Morfologiche e Funzionali. Messina, 21 Maggio 2014
• Corso di aggiornamento su “Rischio e sicurezza nei laboratori scientifici”. Messina, 8 Marzo 2006

1. Anti-Inflammatory  and  Anti-Oxidant  Activity  of  Hidrox®   in  Rotenone-Induced

1. Anti-Inflammatory  and  Anti-Oxidant  Activity  of  Hidrox®   in  Rotenone-Induced

1. Molecular and biochemical changes occurring in the brain after traumatic brain injury and leading to Parkinson's disease: modulation by Hericium erinaceus and Coriolus versicolor

1. Hidrox® roles in neuroprotection: biochemical links between traumatic brain injury

1. Seril-18, a new synthetic molecule, inhibits α-synuclein aggregation in an experimental model of Parkinson’s disease.

1. Hidrox® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain

1. Hidrox® and Endometriosis: Biochemical Evaluation of Oxidative Stress and Pain

1. Hidrox® roles in neuroprotection: biochemical links between traumatic brain injury and Alzheimer’s disease

1. Key mechanisms and potential implications of Hericium erinaceus in NLRP3 inflammasome activation by reactive oxygen species during Alzheimer’s Disease

1. Wnt/β-catenin pathway in fibromyalgia: role of Hidrox

Curriculum

Name: Rosalba 
Surname: Siracusa

Birth place: Barcellona Pozzo di Gotto

Birth date: 09/11/1986

Nationality: Italian

 e-mail: rsiracusa@unime.it

Work Address: University of Messina, Departement of Chemical, Biological, Pharmaceutical and Environmental Science, Italy
 
Native Language: Italian

Other Language: English
 
EDUCATION 
2010: Bachelor’s degree in Biology at the University of Messina, Italy
 
2013: Master degree in Biology, curriculum Biotechnology-Applied Microbiology, University of Messina, Italy
 
2013: Qualification to practice the profession of biologist
 
2017: School of Specialization in Clinical Pathology and Clinical Biochemistry, University of Catania, Italy

2017-2020: PhD student in Applied Biology and Experimental Medicine XXXIII cicle section Experimental Medicine at of Chemical, Biological, Pharmaceutical and        Environmental Sciences, University of Messina, Italy.
 
2019-2020: “Visiting Scientist” at Beth Israel Deaconess Medical Center/Harvard Medical School, Boston, MA, USA. Supervisor: Prof. Leo Otterbein Project: “Examining Carbon Monoxide to Treat Inflammatory Conditions using Experimental Colitis Models”
 
2020: National Scientific Qualification (ASN 2018-2020) for assistant professor in SC 05/E3 Clinical Biochemistry and Clinical Molecular Biology.
  
2021: National Scientific Qualification (ASN 2018-2020) for full professor in SC 05/E3 Clinical Biochemistry and Clinical Molecular Biology.
 
2021-to today: "Senior" researcher, for SC 05/E3, SSD BIO/12 (Clinical Biochemistry and Clinical Molecular Biology), at University of Messina, Italy.
 
 
TEACHING ACTIVITIES
 
June 2020: Seminar for the scientific diffusion day carried out within the didactic/training activities of the Research Doctorate in Applied Biology and Experimental Medicine, Coordinator Prof. Nunziacarla Spanò, University of Messina.
 
February 2021 to today: Member of the examination commission for the discipline "Clinical Biochemistry" (SSD BIO/12) at the Department of Chemical, Biological, Pharmaceutical and Environmental Sciences of the University of Messina Master's Degree Course in Health Biology, Applied Technologies and of Nutrition;
Member of the examination commission for the discipline "Bioinorganic Chemistry and Clinical Biochemistry" (SSD BIO / 12) at the Department of Chemical, Biological, Pharmaceutical and Environmental Sciences of the University of Messina Master's Degree Course in Biology.
 
March 2021: Seminars for the scientific propagation day carried out within the didactic/training activities of the Research Doctorate in Applied Biology and Experimental Medicine (CFU 1), Coordinator Prof.ssa Nunziacarla Spanò, University of Messina.
 
October 2021: Supplementary teaching activity as part of the teaching course in Biochemistry of Food and Nutrition of Metabolic Diseases held by Prof. Daniela Impellizzeri.
 
December 2021: Integrative teaching activity as part of the teaching course in Clinical Biochemistry and Clinical Molecular Biology held by Prof. Daniela Impellizzeri.
 
 
PARTICIPATION IN PROJECTS
 
2014-2015: Research Collaborator as Principal Investigator for the pharmaceutical company "Epitech Group s.p.a." for the project “Research and Development of bio-regulators active on the epigenetic mechanisms of inflammatory processes in chronic and degenerative diseases (BIAM-EPI) (PON01_02512).
 
2015-2016: Research Collaborator as Principal Investigator for the pharmaceutical company "Epitech Group s.p.a." for the project "Innovative therapies for chronic inflammatory, metabolic, neoplastic and geriatric diseases" (TIMING) as part of the POR FESR 2007-2013.
 
2016-2017: Research Collaborator as Principal Investigator for the pharmaceutical company "Epitech Group s.p.a." for the project "Study of the in vivo effects of PEA in various formulations on models of neuro-inflammation of the central nervous system" with reference to the company project called "Evaluation of the efficacy of active ingredients, identified or synthesized, in experimental models of conditions associated with inflammation or neuroinflammation ".
 
2017: Participation in the Research Program of National Interest (PRIN) 2017 entitled "Study of the crosstalk between multiple pathways in the regulation of inflammatory processes in models of chronic and degenerative diseases" protocol 2017 B9NCSX_001, ERC LS7 sector, scientific director Prof. Salvatore Cuzzocrea, University of Messina.
 
 
EXPERTISE
In vivo models: Spinal Cord Injury, Traumatic Brain Injury, Paw Edema, Parkinson Model, Wound Healing, Bleomycin model of pulmonary fibrosis, Pleuritis, Colitis, Vascular Dementia model, Alzheimer's disease models, Autism model, model of kidney ischemia and reperfusion, model of benign prostatic hyperplasia, Endometriosis model, Fibromyalgia model
 
In vitro models: Cellular cultures of glioma (C6), machophages (J774), neuroblastoma (SHSY5Y), monocytes (Thp-1), kidney epithelial (Vero), human embryonic kidney (HEK 293), rabbit corneal (SIRC). 

Ex vivo models: Organotypic slices cultures of spinal cord and brain.
 
Techniques: colorimetric MTT assay, western blot, PCR, ELISA kit, nitrites and nitrates assay, comet assay, preparation and staining of histological samples, immunostaining, immunofluorescence.   
 

MEMBERSHIP OF SCIENTIFIC SOCIETY 
• Italian Society of Pharmacology (SIF) 
• American Society for Pharmacology and Experimental Therapeutics (ASPET)
• Italian Society of Toxicology (SITOX)
• Laboratory Medicine Italian Society of Clinical Biochemistry and Clinical Molecular Biology (S.I.Bio.C.) 
• Italian Society of Biochemistry and Clinical Molecular Biology (SIB)
 
EDITORIAL BOARD
 Journal of Translational Science (IF 2.12)
 
Journal of Clinical Oncology and Cancer Therapy (IF 3.154) 

 Annals of Gastroenterology and Liver Diseases

 Medical Research and Clinical Case Reports 

 Topic Editorial Board: Antioxidants (IF 6.313) 

 Topic Editorial Board: Molecules (IF 4.412)

 Topic Editorial Board: International Journal of Molecular Sciences (IF 5.924)

 Guest Associated Editor: Frontiers in Pharmacology (IF 5.810)

Assistant Guest Editor: Journal: Metabolites (IF 4.932)
Special Issue Title: Metabolites: From Physiology to Pathology

Guest Editor: Journal: Molecules (IF 4.412)
Special Issue Title: Novel Anti-inflammatory and Analgesic agents: Synthesis, Molecular Docking and In Vivo Studies.
 
Co-Editor: Journal: International Journal of Molecular Sciences (IF 5.924)
Special Issue Title: Oxidative Stress: Focusing on New Therapeutic Approaches and Biochemical Markers.
 
Guest Editor: Journal: Foods (IF 4.350)
Special Issue Title: Antioxidant-Rich Foods and Human Health
 
Guest Editor: Journal: Antioxidant (IF 6.313)
Special Issue Title: Antioxidant Compounds Recovered from Food Wastes
 
Guest Editor: Journal: Biomedicine (IF 6.081)
Special Issue Title: Molecular Pathology and Biomarkers of Neurodegenerative Diseases
 
 
AWARDS
2019: “SIF” Grant for PhD students, for a research period of 1 year to Harvard Medical School, Boston, MA. Supervisor: Prof. Otterbein L.; Project: “Examining Carbon Monoxide to Treat Inflammatory Conditions using Experimental Colitis Models”
 
2021: Participation scholarship to the 45th Virtual FEBS Congress.
 
 
Indicators according to Scopus
Number of publications: 123
H-Index: 32
Number of citations: 2288
 
 

SCIENTIFIC RESEARCH
 
PUBLICATION LIST 
 
1.     Paterniti, I.; Cordaro, M.; Campolo, M.; Siracusa, R.; Cornelius, C.; Navarra, M.; Cuzzocrea, S.; Esposito, E. Neuroprotection by association of palmitoylethanolamide with luteolin in experimental alzheimer’s disease models: The control of neuroinflammation. CNS Neurol. Disord. - Drug Targets 2014, 13, 1530–1541, doi:10.2174/1871527313666140806124322. IF: 4.388
 
2.     Impellizzeri, D.; Bruschetta, G.; Cordaro, M.; Crupi, R.; Siracusa, R.; Esposito, E.; Cuzzocrea, S. Micronized/ultramicronized palmitoylethanolamide displays superior oral efficacy compared to nonmicronized palmitoylethanolamide in a rat model of inflammatory pain. J. Neuroinflammation 2014, 11, doi:10.1186/s12974-014-0136-0. IF: 8.322
 
3.     Impellizzeri, D.; Talero, E.; Siracusa, R.; Alcaide, A.; Cordaro, M.; Maria Zubelia, J.; Bruschetta, G.; Crupi, R.; Esposito, E.; Cuzzocrea, S.; et al. Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice. Br. J. Nutr. 2015, 114, 853–865, doi:10.1017/S0007114515002597. IF: 3.718
 
4.     Impellizzeri, D.; Bruschetta, G.; Ahmad, A.; Crupi, R.; Siracusa, R.; Di Paola, R.; Paterniti, I.; Prosdocimi, M.; Esposito, E.; Cuzzocrea, S. Effects of palmitoylethanolamide and silymarin combination treatment in an animal model of kidney ischemia and reperfusion. Eur. J. Pharmacol. 2015, 762, 136–149, doi:10.1016/j.ejphar.2015.05.010. IF: 4.432
 
5.      Siracusa, R.*; Paterniti, I.; Impellizzeri, D.; Cordaro, M.; Crupi, R.; Navarra, M.; Cuzzocrea, S.; Esposito, E. The association of palmitoylethanolamide with luteolin decreases neuroinflammation and stimulates autophagy in Parkinson’s disease model. CNS Neurol. Disord. - Drug Targets 2015, 14, 1350–1365. IF: 4.388
 
6.      Paterniti, I.; Di Paola, R.; Campolo, M.; Siracusa, R.; Cordaro, M.; Bruschetta, G.; Tremolada, G.; Maestroni, A.; Bandello, F.; Esposito, E.; et al. Palmitoylethanolamide treatment reduces retinal inflammation in streptozotocin-induced diabetic rats. Eur. J. Pharmacol. 2015, 769, 313–323, doi:10.1016/j.ejphar.2015.11.035. IF: 4.432
 
7.      Trovato, A.*; Siracusa, R.*; Di Paola, R.; Scuto, M.; Ontario, M.L.; Bua, O.; Di Mauro, P.; Toscano, M.A.; Petralia, C.C.T.; Maiolino, L.; et al. Redox modulation of cellular stress response and lipoxin A4 expression by Hericium Erinaceus in rat brain: Relevance to Alzheimer’s disease pathogenesis. Immun. Ageing 2016, 13, doi:10.1186/s12979-016-0078-8. IF: 6.400
 
8.      Cordaro, M.; Impellizzeri, D.; Paterniti, I.; Bruschetta, G.; Siracusa, R.; De Stefano, D.; Cuzzocrea, S.; Esposito, E. Neuroprotective effects of Co-UltraPEALut on secondary inflammatory process and autophagy involved in traumatic brain injury. J. Neurotrauma 2016, 33, 132–146, doi:10.1089/neu.2014.3460. IF: 5.269
 
9.      Cordaro, M.; Impellizzeri, D.; Bruschetta, G.; Siracusa, R.; Crupi, R.; Di Paola, R.; Esposito, E.; Cuzzocrea, S. A novel protective formulation of Palmitoylethanolamide in experimental model of contrast agent induced nephropathy. Toxicol. Lett. 2016, 240, 10–21, doi:10.1016/j.toxlet.2015.10.006. IF: 4.374
 
10.   Trovato Salinaro, A.; Siracusa, R.; Di Paola, R.; Scuto, M.; Fronte, V.; Koverech, G.; Luca, M.; Serra, A.; Toscano, M.A.; Petralia, A.; et al. Redox modulation of cellular stress response and lipoxin A4 expression by Coriolus versicolor in rat brain: Relevance to Alzheimer’s disease pathogenesis. Neurotoxicology 2016, 53, 350–358, doi:10.1016/j.neuro.2015.09.012. IF: 4.294
 
11.   Crupi, R.; Impellizzeri, D.; Bruschetta, G.; Cordaro, M.; Paterniti, I.; Siracusa, R.; Cuzzocrea, S.; Esposito, E. Co-ultramicronized palmitoylethanolamide/luteolin promotes neuronal regeneration after spinal cord injury. Front. Pharmacol. 2016, 7, doi:10.3389/fphar.2016.00047. IF: 5.811
 
12.  Esposito, E.; Impellizzeri, D.; Bruschetta, G.; Cordaro, M.; Siracusa, R.; Gugliandolo, E.; Crupi, R.; Cuzzocrea, S. A new co-micronized composite containing palmitoylethanolamide and polydatin shows superior oral efficacy compared to their association in a rat paw model of carrageenan-induced inflammation. Eur. J. Pharmacol. 2016, 782, 107–118, doi:10.1016/j.ejphar.2016.03.033. IF: 4.432
 
13.  Di Paola, R.; Cordaro, M.; Crupi, R.; Siracusa, R.; Campolo, M.; Bruschetta, G.; Fusco, R.; Pugliatti, P.; Esposito, E.; Cuzzocrea, S. Protective Effects of Ultramicronized Palmitoylethanolamide (PEA-um) In Myocardial Ischaemia And Reperfusion Injury In VIVO. Shock 2016, 46, 202–213, doi:10.1097/SHK.0000000000000578. IF: 3.454
 
14.  Siracusa, R.*; Paterniti, I.; Bruschetta, G.; Cordaro, M.; Impellizzeri, D.; Crupi, R.; Cuzzocrea, S.; Esposito, E. The Association of Palmitoylethanolamide with Luteolin Decreases Autophagy in Spinal Cord Injury. Mol. Neurobiol. 2016, 53, 3783–3792, doi:10.1007/s12035-015-9328-6. IF: 5.590
 
15.  Di Paola, R.; Impellizzeri, D.; Fusco, R.; Cordaro, M.; Siracusa, R.; Crupi, R.; Esposito, E.; Cuzzocrea, S. Ultramicronized palmitoylethanolamide (PEA-um®) in the treatment of idiopathic pulmonary fibrosis. Pharmacol. Res. 2016, 111, 405–412, doi:10.1016/j.phrs.2016.07.010. IF: 7.658
 
16.  Cordaro, M.; Impellizzeri, D.; Gugliandolo, E.; Siracusa, R.; Crupi, R.; Esposito, E.; Cuzzocrea, S. Adelmidrol, a palmitoylethanolamide analogue, as a new pharmacological treatment for the management of inflammatory bowel disease. Mol. Pharmacol. 2016, 90, 549–561, doi:10.1124/mol.116.105668. IF: 4.436
 
17.  Bertolino, B.; Crupi, R.; Impellizzeri, D.; Bruschetta, G.; Cordaro, M.; Siracusa, R.; Esposito, E.; Cuzzocrea, S. Beneficial Effects of Co-Ultramicronized Palmitoylethanolamide/Luteolin in a Mouse Model of Autism and in a Case Report of Autism. CNS Neurosci. Ther. 2017, 23, 87–98, doi:10.1111/cns.12648. IF: 5.243
 
18.  Paterniti, I.*; Campolo, M.*; Siracusa, R.*; Cordaro, M.; Di Paola, R.; Calabrese, V.; Navarra, M.; Cuzzocrea, S.; Esposito, E. Liver X receptors activation, through TO901317 binding, reduces neuroinflammation in Parkinson’s disease. PLoS One 2017, 12, doi:10.1371/journal.pone.0174470. IF: 3.240
 
19.  Cordaro, M.*; Paterniti, I.*; Siracusa, R.; Impellizzeri, D.; Esposito, E.; Cuzzocrea, S. KU0063794, a Dual mTORC1 and mTORC2 Inhibitor, Reduces Neural Tissue Damage and Locomotor Impairment After Spinal Cord Injury in Mice. Mol. Neurobiol. 2017, 54, 2415–2427, doi:10.1007/s12035-016-9827-0. IF: 5.590
 
20.  Petrosino, S.; Campolo, M.; Impellizzeri, D.; Paterniti, I.; Allarà, M.; Gugliandolo, E.; D’Amico, R.; Siracusa, R.; Cordaro, M.; Esposito, E.; et al. 2-Pentadecyl-2-oxazoline, the oxazoline of PEA, modulates carrageenan-induced acute inflammation. Front. Pharmacol. 2017, 8, doi:10.3389/fphar.2017.00308. IF: 5.811
 
21.  Siracusa, R.*; Impellizzeri, D.; Cordaro, M.; Crupi, R.; Esposito, E.; Petrosino, S.; Cuzzocrea, S. Anti-inflammatory and neuroprotective effects of co-ultraPEALut in a mouse model of vascular dementia. Front. Neurol. 2017, 8, doi:10.3389/fneur.2017.00233. IF: 4.003
 
22.  Cordaro, M.; Impellizzeri, D.; Siracusa, R.; Gugliandolo, E.; Fusco, R.; Inferrera, A.; Esposito, E.; Di Paola, R.; Cuzzocrea, S. Effects of a co-micronized composite containing palmitoylethanolamide and polydatin in an experimental model of benign prostatic hyperplasia. Toxicol. Appl. Pharmacol. 2017, 329, 231–240, doi:10.1016/j.taap.2017.06.005. IF: 4.219
 
23.  Paterniti, I.; Impellizzeri, D.; Cordaro, M.; Siracusa, R.; Bisignano, C.; Gugliandolo, E.; Carughi, A.; Esposito, E.; Mandalari, G.; Cuzzocrea, S. The anti-inflammatory and antioxidant potential of pistachios (Pistacia vera L.) in vitro and in vivo. Nutrients 2017, 9, doi:10.3390/nu9080915. IF: 5.719
 
24.  Impellizzeri, D.; Cordaro, M.; Bruschetta, G.; Siracusa, R.; Crupi, R.; Esposito, E.; Cuzzocrea, S. N-Palmitoylethanolamine-Oxazoline as a New Therapeutic Strategy to Control Neuroinflammation: Neuroprotective Effects in Experimental Models of Spinal Cord and Brain Injury. J. Neurotrauma 2017, 34, 2609–2623, doi:10.1089/neu.2016.4808. IF: 5.269
 
25.  Paterniti, I.; Campolo, M.; Cordaro, M.; Impellizzeri, D.; Siracusa, R.; Crupi, R.; Esposito, E.; Cuzzocrea, S. PPAR-α Modulates the Anti-Inflammatory Effect of Melatonin in the Secondary Events of Spinal Cord Injury. Mol. Neurobiol. 2017, 54, 5973–5987, doi:10.1007/s12035-016-0131-9. IF: 5.590
 
26.  Gugliandolo, E.; D’Amico, R.; Cordaro, M.; Fusco, R.; Siracusa, R.; Crupi, R.; Impellizzeri, D.; Cuzzocrea, S.; Di Paola, R. Neuroprotective effect of artesunate in experimental model of traumatic brain injury. Front. Neurol. 2018, 9, doi:10.3389/fneur.2018.00590. IF: 4.003
 
27.  Akki, R.*; Siracusa, R.*; Morabito, R.; Remigante, A.; Campolo, M.; Errami, M.; La Spada, G.; Cuzzocrea, S.; Marino, A. Neuronal-like differentiated SH-SY5Y cells adaptation to a mild and transient H₂O₂-induced oxidative stress. Cell Biochem. Funct. 2018, 36, 56–64, doi:10.1002/cbf.3317. IF: 3.685
 
28.  Siracusa, R.*; Paterniti, I.; Cordaro, M.; Crupi, R.; Bruschetta, G.; Campolo, M.; Cuzzocrea, S.; Esposito, E. Neuroprotective Effects of Temsirolimus in Animal Models of Parkinson’s Disease. Mol. Neurobiol. 2018, 55, 2403–2419, doi:10.1007/s12035-017-0496-4. IF: 5.590
 
29.  Petrosino, S.; Cordaro, M.; Verde, R.; Moriello, A.S.; Marcolongo, G.; Schievano, C.; Siracusa, R.; Piscitelli, F.; Peritore, A.F.; Crupi, R.; et al. Oral ultramicronized palmitoylethanolamide: Plasma and tissue levels and spinal anti-hyperalgesic effect. Front. Pharmacol. 2018, 9, doi:10.3389/fphar.2018.00249. IF: 5.811
 
30.  Paterniti, I.; Campolo, M.; Cordaro, M.; Siracusa, R.; Filippone, A.; Esposito, E.; Cuzzocrea, S. Effects of different natural extracts in an experimental model of benign prostatic hyperplasia (BPH). Inflamm. Res. 2018, 67, 617–626, doi:10.1007/s00011-018-1152-9. IF: 4.575
 
31.  Fusco, R.; D’amico, R.; Cordaro, M.; Gugliandolo, E.; Siracusa, R.; Peritore, A.F.; Crupi, R.; Impellizzeri, D.; Cuzzocrea, S.; Di Paola, R. Absence of formyl peptide receptor 1 causes endometriotic lesion regression in a mouse model of surgically-induced endometriosis. Oncotarget 2018, 9, 31355–31366, doi:10.18632/oncotarget.25823. IF: 5.168
 
32.  Ostardo, E.; Impellizzeri, D.; Cervigni, M.; Porru, D.; Sommariva, M.; Cordaro, M.; Siracusa, R.; Fusco, R.; Gugliandolo, E.; Crupi, R.; et al. Adelmidrol + sodium hyaluronate in IC/BPS or conditions associated to chronic urothelial inflammation. A translational study. Pharmacol. Res. 2018, 134, 16–30, doi:10.1016/j.phrs.2018.05.013. IF: 7.658
 
33.  Siracusa, R.*; Impellizzeri, D.; Cordaro, M.; Gugliandolo, E.; Peritore, A.F.; Di Paola, R.; Cuzzocrea, S. Topical application of adelmidrol + trans-traumatic acid enhances skin wound healing in a streptozotocin-induced diabetic mouse model. Front. Pharmacol. 2018, 9, doi:10.3389/fphar.2018.00871. IF: 5.810
 
34.  Impellizzeri, D.; Siracusa, R.; Cordaro, M.; Peritore, A.F.; Gugliandolo, E.; Mancuso, G.; Midiri, A.; Di Paola, R.; Cuzzocrea, S. Therapeutic potential of dinitrobenzene sulfonic acid (DNBS)-induced colitis in mice by targeting IL-1β and IL-18. Biochem. Pharmacol. 2018, 155, 150–161, doi:10.1016/j.bcp.2018.06.029. IF: 5.858
 
35.  Gugliandolo, E.; D’Amico, R.; Cordaro, M.; Fusco, R.; Siracusa, R.; Crupi, R.; Impellizzeri, D.; Cuzzocrea, S.; Di Paola, R. Effect of PEA-OXA on neuropathic pain and functional recovery after sciatic nerve crush 11 Medical and Health Sciences 1109 Neurosciences. J. Neuroinflammation 2018, 15, doi:10.1186/s12974-018-1303-5. IF: 7.957
 
36.  Crupi, R.; Impellizzeri, D.; Cordaro, M.; Siracusa, R.; Casili, G.; Evangelista, M.; Cuzzocrea, S. N-palmitoylethanolamide Prevents Parkinsonian Phenotypes in Aged Mice. Mol. Neurobiol. 2018, 55, 8455–8472, doi:10.1007/s12035-018-0959-2. IF: 5.590
 
37.  Cordaro, M.*; Siracusa, R.*; Crupi, R.; Impellizzeri, D.; Peritore, A.F.; D’Amico, R.; Gugliandolo, E.; Di Paola, R.; Cuzzocrea, S. 2-Pentadecyl-2-Oxazoline Reduces Neuroinflammatory Environment in the MPTP Model of Parkinson Disease. Mol. Neurobiol. 2018, 55, 9251–9266, doi:10.1007/s12035-018-1064-2. IF: 5.590
 
38.  Campolo, M.*; Siracusa, R.*; Cordaro, M.; Filippone, A.; Gugliandolo, E.; Peritore, A.F.; Impellizzeri, D.; Crupi, R.; Paterniti, I.; Cuzzocrea, S. The association of adelmidrol with sodium hyaluronate displays beneficial properties against bladder changes following spinal cord injury in mice. PLoS One 2019, 14, doi:10.1371/journal.pone.0208730. IF: 3.240
 
39.  Siracusa, R.*; Fusco, R.; Cuzzocrea, S. Astrocytes: Role and functions in brain pathologies. Front. Pharmacol. 2019, 10, doi:10.3389/fphar.2019.01114. IF: 5.810
 
40.  Lunardelli, M.L.*; Crupi, R.*; Siracusa, R.*; Cocuzza, G.; Cordaro, M.; Martini, E.; Impellizzeri, D.; Di Paola, R.; Cuzzocrea, S. Co-ultraPEALut: Role in preclinical and clinical delirium manifestations. CNS Neurol. Disord. - Drug Targets 2019, 18, 530–554, doi:10.2174/1871527318666190617162041. IF: 4.388
 
41.  Akki, R.; Siracusa, R.; Cordaro, M.; Remigante, A.; Morabito, R.; Errami, M.; Marino, A. Adaptation to oxidative stress at cellular and tissue level. Arch. Physiol. Biochem. 2019, doi:10.1080/13813455.2019.1702059. IF: 2.952
 
42.  Campolo, M.*; Paterniti, I.*; Siracusa, R.; Filippone, A.; Esposito, E.; Cuzzocrea, S. TLR4 absence reduces neuroinflammation and inflammasome activation in Parkinson’s diseases in vivo model. Brain. Behav. Immun. 2019, 76, 236–247, doi:10.1016/j.bbi.2018.12.003. IF: 7.217
 
43.  D’amico, R.; Fusco, R.; Gugliandolo, E.; Cordaro, M.; Siracusa, R.; Impellizzeri, D.; Peritore, A.F.; Crupi, R.; Cuzzocrea, S.; Di Paola, R. Effects of a new compound containing Palmitoylethanolamide and Baicalein in myocardial ischaemia/reperfusion injury in vivo. Phytomedicine 2019, 54, 27–42, doi:10.1016/j.phymed.2018.09.191. IF: 5.340
 
44.  Impellizzeri, D.; Siracusa, R.; Cordaro, M.; Crupi, R.; Peritore, A.F.; Gugliandolo, E.; D’Amico, R.; Petrosino, S.; Evangelista, M.; Di Paola, R.; et al. N-Palmitoylethanolamine-oxazoline (PEA-OXA): A new therapeutic strategy to reduce neuroinflammation, oxidative stress associated to vascular dementia in an experimental model of repeated bilateral common carotid arteries occlusion. Neurobiol. Dis. 2019, 125, 77–91, doi:10.1016/j.nbd.2019.01.007. IF: 5.996
 
45.  Peritore, A.F.*; Siracusa, R.*; Crupi, R.; Cuzzocrea, S. Therapeutic efficacy of palmitoylethanolamide and its new formulations in synergy with different antioxidant molecules present in diets. Nutrients 2019, 11, doi:10.3390/nu11092175. IF: 5.717
 
46.  Impellizzeri, D.; Peritore, A.F.; Cordaro, M.; Gugliandolo, E.; Siracusa, R.; Crupi, R.; D’Amico, R.; Fusco, R.; Evangelista, M.; Cuzzocrea, S.; et al. The neuroprotective effects of micronized PEA (PEA-m) formulation on diabetic peripheral neuropathy in mice. FASEB J. 2019, 33, 11364–11380, doi:10.1096/fj.201900538R. IF: 5.191
 
47.  Fusco, R.; Scuto, M.; Cordaro, M.; D’Amico, R.; Gugliandolo, E.; Siracusa, R.; Peritore, A.F.; Crupi, R.; Impellizzeri, D.; Cuzzocrea, S.; et al. N-palmitoylethanolamide-oxazoline protects against middle cerebral artery occlusion injury in diabetic rats by regulating the SIRT1 pathway. Int. J. Mol. Sci. 2019, 20, doi:10.3390/ijms20194845. IF: 5.923
 
48.  Cordaro, M.; Siracusa, R.; Impellizzeri, D.; D’Amico, R.; Peritore, A.F.; Crupi, R.; Gugliandolo, E.; Fusco, R.; Di Paola, R.; Schievano, C.; et al. Safety and efficacy of a new micronized formulation of the ALIAmide palmitoylglucosamine in preclinical models of inflammation and osteoarthritis pain. Arthritis Res. Ther. 2019, 21, doi:10.1186/s13075-019-2048-y. IF: 5.156
 
49.  Fusco, R.*; Siracusa, R.*; D’amico, R.*; Peritore, A.F.; Cordaro, M.; Gugliandolo, E.; Crupi, R.; Impellizzeri, D.; Cuzzocrea, S.; Paola, R.D. Melatonin plus folic acid treatment ameliorates reserpine-induced fibromyalgia: An evaluation of pain, oxidative stress, and inflammation. Antioxidants 2019, 8, doi:10.3390/antiox8120628. IF: 5.014
 
50.  Crupi, R.; Impellizzeri, D.; Gugliandolo, E.; Cordaro, M.; Siracusa, R.; Britti, D.; Cuzzocrea, S.; Di Paola, R. Effect of Tempol, a Membrane-Permeable Free Radical Scavenger, on in Vitro Model of Eye Inflammation on Rabbit Corneal Cells. J. Ocul. Pharmacol. Ther. 2019, 35, 571–577, doi:10.1089/jop.2019.0016. IF: 2.671
 
51.  Rapa, S.F.; Waltenberger, B.; Di Paola, R.; Adesso, S.; Siracusa, R.; Peritore, A.F.; D’Amico, R.; Autore, G.; Cuzzocrea, S.; Stuppner, H.; et al. Plumericin prevents intestinal inflammation and oxidative stress in vitro and in vivo. FASEB J. 2020, 34, 1576–1590, doi:10.1096/fj.201902040R. IF: 5.191
 
52.  Peritore, A.F.; Crupi, R.; Scuto, M.; Gugliandolo, E.; Siracusa, R.; Impellizzeri, D.; Cordaro, M.; D’amico, R.; Fusco, R.; Paola, R.D.; et al. The role of annexin A1 and formyl peptide receptor 2/3 signaling in chronic corticosterone-induced depression-like behaviors and impairment in hippocampal-dependent memory. CNS Neurol. Disord. - Drug Targets 2020, 19, 27–43, doi:10.2174/1871527319666200107094732. IF: 4.388
 
53.  Crupi, R.; Gugliandolo, E.; Siracusa, R.; Impellizzeri, D.; Cordaro, M.; Di Paola, R.; Britti, D.; Cuzzocrea, S. N-acetyl-L-cysteine reduces Leishmania amazonensis-induced inflammation in BALB/c mice. BMC Vet. Res. 2020, 16, doi:10.1186/s12917-020-2234-9. IF: 2.741
 
54.  Siracusa, R.*; Impellizzeri, D.; Cordaro, M.; Peritore, A.F.; Gugliandolo, E.; D’Amico, R.; Fusco, R.; Crupi, R.; Rizzarelli, E.; Cuzzocrea, S.; et al. The protective effect of new carnosine-hyaluronic acid conjugate on the inflammation and cartilage degradation in the experimental model of osteoarthritis. Appl. Sci. 2020, 10, doi:10.3390/app10041324. IF: 2.679
 
55.  Cordaro, M.*; Scuto, M.*; Siracusa, R.; D’amico, R.; Filippo Peritore, A.; Gugliandolo, E.; Fusco, R.; Crupi, R.; Impellizzeri, D.; Pozzebon, M.; et al. Effect of N-palmitoylethanolamine-oxazoline on comorbid neuropsychiatric disturbance associated with inflammatory bowel disease. FASEB J. 2020, 34, 4085–4106, doi:10.1096/fj.201901584RR. IF: 5.191
 
56.  Siracusa, R.*; Fusco, R.; Peritore, A.F.; Cordaro, M.; D’amico, R.; Genovese, T.; Gugliandolo, E.; Crupi, R.; Smeriglio, A.; Mandalari, G.; et al. The antioxidant and anti-inflammatory properties of Anacardium occidentale l. Cashew nuts in a mouse model of colitis. Nutrients 2020, 12, doi:10.3390/nu12030834. IF: 5.717
 
57.  D’amico, R.*; Fusco, R.*; Cordaro, M.*; Siracusa, R.; Peritore, A.F.; Gugliandolo, E.; Crupi, R.; Scuto, M.; Cuzzocrea, S.; Di Paola, R.; et al. Modulation of NLRP3 inflammasome through formyl peptide receptor 1 (Fpr-1) pathway as a new therapeutic target in bronchiolitis obliterans syndrome. Int. J. Mol. Sci. 2020, 21, doi:10.3390/ijms21062144. IF: 5.923
 
58.  Crupi, R.*; Palma, E.*; Siracusa, R.*; Fusco, R.; Gugliandolo, E.; Cordaro, M.; Impellizzeri, D.; De Caro, C.; Calzetta, L.; Cuzzocrea, S.; et al. Protective Effect of Hydroxytyrosol Against Oxidative Stress Induced by the Ochratoxin in Kidney Cells: in vitro and in vivo Study. Front. Vet. Sci. 2020, 7, doi:10.3389/fvets.2020.00136. IF: 3.412
 
59.  Gugliandolo, E.; Palma, E.; Peritore, A.F.; Siracusa, R.; D’amico, R.; Fusco, R.; Licata, P.; Crupi, R. Effect of artesunate on leishmania amazonesis induced neuroinflammation and nociceptive behavior in male BALB/C mice. Animals 2020, 10, doi:10.3390/ani10040557. IF: 2.752
 
60.  Impellizzeri, D.*; Siracusa, R.*; Cordaro, M.; Peritore, A.F.; Gugliandolo, E.; D’amico, R.; Fusco, R.; Crupi, R.; Rizzarelli, E.; Cuzzocrea, S.; et al. Protective effect of a new hyaluronic acid -carnosine conjugate on the modulation of the inflammatory response in mice subjected to collagen-induced arthritis. Biomed. Pharmacother. 2020, 125, doi:10.1016/j.biopha.2020.110023. IF: 6.529
 
61.  Peritore, A.F.*; Siracusa, R.*; Fusco, R.*; Gugliandolo, E.; D’amico, R.; Cordaro, M.; Crupi, R.; Genovese, T.; Impellizzeri, D.; Cuzzocrea, S.; et al. Ultramicronized palmitoylethanolamide and paracetamol, a new association to relieve hyperalgesia and pain in a sciatic nerve injury model in rat. Int. J. Mol. Sci. 2020, 21, doi:10.3390/ijms21103509. IF: 5.923
 
62.  Fusco, R.*; Siracusa, R.*; Peritore, A.F.; Gugliandolo, E.; Genovese, T.; D’amico, R.; Cordaro, M.; Crupi, R.; Mandalari, G.; Impellizzeri, D.; et al. The role of cashew (Anacardium occidentale L.) nuts on an experimental model of painful degenerative joint disease. Antioxidants 2020, 9, 1–12, doi:10.3390/antiox9060511. IF: 6.312
 
63.  Fusco, R.*; Siracusa, R.*; Genovese, T.; Cuzzocrea, S.; Paola, R.D. Focus on the role of NLRP3 inflammasome in diseases. Int. J. Mol. Sci. 2020, 21, 1–25, doi:10.3390/ijms21124223. IF: 4.556
 
64.  Fusco, R.; Cordaro, M.; Genovese, T.; Impellizzeri, D.; Siracusa, R.; Gugliandolo, E.; Peritore, A.F.; D’amico, R.; Crupi, R.; Cuzzocrea, S.; et al. Adelmidrol: A new promising antioxidant and anti-inflammatory therapeutic tool in pulmonary fibrosis. Antioxidants 2020, 9, 1–14, doi:10.3390/antiox9070601. IF: 6.312
 
65.  Cordaro, M.*; Siracusa, R.*; Fusco, R.*; D’amico, R.; Peritore, A.F.; Gugliandolo, E.; Genovese, T.; Scuto, M.; Crupi, R.; Mandalari, G.; et al. Cashew (Anacardium occidentale L.) nuts counteract oxidative stress and inflammation in an acute experimental model of carrageenan-induced paw edema. Antioxidants 2020, 9, 1–19, doi:10.3390/antiox9080660. IF: 6.312
 
66.  Fusco, R.*; Cordaro, M.*; Siracusa, R.; Peritore, A.F.; D’amico, R.; Licata, P.; Crupi, R.; Gugliandolo, E. Effects of hydroxytyrosol against lipopolysaccharide-induced inflammation and oxidative stress in bovine mammary epithelial cells: A natural therapeutic tool for bovine mastitis. Antioxidants 2020, 9, 1–15, doi:10.3390/antiox9080693. IF: 6.312
 
67.  Siracusa, R.*; Scuto, M.*; Fusco, R.; Trovato, A.; Ontario, M.L.; Crea, R.; Di Paola, R.; Cuzzocrea, S.; Calabrese, V. Anti-inflammatory and anti-oxidant activity of hidrox® in rotenone-induced Parkinson’s disease in mice. Antioxidants 2020, 9, 1–19, doi:10.3390/antiox9090824. IF: 6.312
 
68.  Fusco, R.*; Cordaro, M.*; Siracusa, R.; D’amico, R.; Genovese, T.; Gugliandolo, E.; Filippo Peritore, A.; Crupi, R.; Impellizzeri, D.; Cuzzocrea, S.; et al. Biochemical evaluation of the antioxidant effects of hydroxytyrosol on pancreatitis-associated gut injury. Antioxidants 2020, 9, 1–18, doi:10.3390/antiox9090781. IF: 6.312
 
69.  Fusco, R.*; Gugliandolo, E.*; Siracusa, R.*; Scuto, M.; Cordaro, M.; D’amico, R.; Evangelista, M.; Peli, A.; Peritore, A.F.; Impellizzeri, D.; et al. Formyl peptide receptor 1 signaling in acute inflammation and neural differentiation induced by traumatic brain injury. Biology (Basel). 2020, 9, 1–30, doi:10.3390/biology9090238. IF: 5.079
 
70.  Gugliandolo, E.*; Cordaro, M.*; Siracusa, R.; D’amico, R.; Peritore, A.F.; Genovese, T.; Impellizzeri, D.; Paola, R.D.; Crupi, R.; Cuzzocrea, S.; et al. Novel combination of cox-2 inhibitor and antioxidant therapy for modulating oxidative stress associated with intestinal ischemic reperfusion injury and endotoxemia. Antioxidants 2020, 9, 1–12, doi:10.3390/antiox9100930. IF: 6.312
 
71.  Fusco, R.*; Cordaro, M.*; Siracusa, R.; Peritore, A.F.; Gugliandolo, E.; Genovese, T.; D’Amico, R.; Crupi, R.; Smeriglio, A.; Mandalari, G.; et al. Consumption of anacardium occidentale L. (Cashew Nuts) Inhibits oxidative stress through modulation of the Nrf2/HO−1 and NF-kB pathways. Molecules 2020, 25, doi:10.3390/molecules25194426. IF: 4.411
 
72.  Cordaro, M.*; Fusco, R.*; D’amico, R.*; Siracusa, R.; Peritore, A.F.; Gugliandolo, E.; Genovese, T.; Crupi, R.; Mandalari, G.; Cuzzocrea, S.; et al. Cashew (Anacardium occidentale l.) nuts modulate the nrf2 and nlrp3 pathways in pancreas and lung after induction of acute pancreatitis by cerulein. Antioxidants 2020, 9, 1–16, doi:10.3390/antiox9100992. IF: 6.312
 
 
73.  Gugliandolo, E.; Peritore, A.F.; Impellizzeri, D.; Cordaro, M.; Siracusa, R.; Fusco, R.; D’amico, R.; Di Paola, R.; Schievano, C.; Cuzzocrea, S.; et al. Dietary supplementation with palmitoyl- glucosamine co-micronized with curcumin relieves osteoarthritis pain and benefits joint mobility. Animals 2020, 10, 1–17, doi:10.3390/ani10101827. IF: 2.752
 
74.  Casili, G.; Lanza, M.; Campolo, M.; Siracusa, R.; Paterniti, I.; Ardizzone, A.; Scuderi, S.A.; Cuzzocrea, S.; Esposito, E. Synergic therapeutic potential of PEA-Um treatment and NAAA enzyme silencing in the management of neuroinflammation. Int. J. Mol. Sci. 2020, 21, 1–13, doi:10.3390/ijms21207486. IF: 5.923
 
75.  Fusco, R.*; Siracusa, R.*; D’amico, R.; Cordaro, M.; Genovese, T.; Gugliandolo, E.; Peritore, A.F.; Crupi, R.; Di Paola, R.; Cuzzocrea, S.; et al. Mucosa-associated lymphoid tissue lymphoma translocation 1 inhibitor as a novel therapeutic tool for lung injury. Int. J. Mol. Sci. 2020, 21, 1–14, doi:10.3390/ijms21207761. IF: 5.923
 
76.  Siracusa, R.*; Fusco, R.; Cordaro, M.; Peritore, A.F.; D’amico, R.; Gugliandolo, E.; Crupi, R.; Genovese, T.; Evangelista, M.; Di Paola, R.; et al. The protective effects of pre-and post-administration of micronized palmitoylethanolamide formulation on postoperative pain in rats. Int. J. Mol. Sci. 2020, 21, 1–17, doi:10.3390/ijms21207700. IF: 5.923
 
77.  D’Amico, R.*; Siracusa, R.*; Fusco, R.; Cordaro, M.; Genovese, T.; Peritore, A.F.; Gugliandolo, E.; Crupi, R.; Impellizzeri, D.; Cuzzocrea, S.; et al. Protective effects of Colomast®, A New Formulation of Adelmidrol and Sodium Hyaluronate, in A Mouse Model of Acute Restraint Stress. Int. J. Mol. Sci. 2020, 21, doi:10.3390/ijms21218136. IF: 5.923
 
78.  Gugliandolo, E.; Fusco, R.; Licata, P.; Peritore, A.F.; D’amico, R.; Cordaro, M.; Siracusa, R.; Cuzzocrea, S.; Crupi, R. Protective effect of hydroxytyrosol on lps-induced inflammation and oxidative stress in bovine endometrial epithelial cell line. Vet. Sci. 2020, 7, 1–10, doi:10.3390/vetsci7040161. IF: 2.304
 
79.  Cordaro, M.*; Siracusa, R.*; Fusco, R.; Cuzzocrea, S.; Di Paola, R.; Impellizzeri, D. Involvements of hyperhomocysteinemia in neurological disorders. Metabolites 2021, 11, 1–19, doi:10.3390/metabo11010037. IF: 4.932
 
80.  Rapa, S.F.; Di Paola, R.; Cordaro, M.; Siracusa, R.; D’amico, R.; Fusco, R.; Autore, G.; Cuzzocrea, S.; Stuppner, H.; Marzocco, S. Plumericin protects against experimental inflammatory bowel disease by restoring intestinal barrier function and reducing apoptosis. Biomedicines 2021, 9, 1–16, doi:10.3390/biomedicines9010067. IF: 6.081
 
81.  Cordaro, M.; D’Amico, R.; Morabito, R.; Fusco, R.; Siracusa, R.; Peritore, A.F.; Impellizzeri, D.; Genovese, T.; Crupi, R.; Gugliandolo, E.; Marino, A.; Di Paola, R.; Cuzzocrea, S.; et al. Physiological and Biochemical Changes in NRF2 Pathway in Aged Animals Subjected to Brain Injury. Cell Physiol Biochem 2021, 55:160-179, doi: 10.33594/000000353. IF: 5.500
 
82.  D'Amico R., Monaco F., Fusco R., Peritore A.F., Genovese T., Impellizzeri D., Crupi R., Sforza A.M., Gugliandolo E., Siracusa R.*, Cuzzocrea S., Cordaro M. and Di Paola R.; et al. Exposure to Atrazine induces lung inflammation through Nrf2-HO1 and Beclin 1/LC3 pathways. Cellular Physiology and Biochemistry, 2021, 55(4), pp. 413–427; doi:10.33594/000000393. IF: 5.500
 
83.   Fusco R.*; Siracusa R.*; Gugliandolo E.; Peritore A.F.; D'Amico R.; Cordaro M.; Crupi R.; Impellizzeri D.; Gomiero C.; Cuzzocrea S.; Di Paola R.; et al. Micro Composite Palmitoylethanolamide/Rutin Reduces Vascular Injury through Modulation of the Nrf2/HO-1 and NF-kB Pathways. Current Medicinal Chemistry, 2021, 28(30), pp. 6287–6302 doi: 10.2174/0929867328666210329120213. IF: 4.530
 
84.   D’Amico R., Monaco F., Fusco R., Siracusa R., Impellizzeri D., Peritore A.F., Crupi R., Gugliandolo E., Cuzzocrea S., Di Paola R., Genovese T., Cordaro M.; et al. Atrazine Inhalation Worsen Pulmonary Fibrosis Regulating the Nuclear Factor-Erythroid 2-Related Factor (Nrf2) Pathways Inducing Brain Comorbidities. Cellular Physiology and Biochemistry, 2021, 55(6), pp. 704–725; doi: 10.33594/000000471. IF: 5.500
 
85.   Peritore, A.F.; D’amico, R.; Cordaro, M.; Siracusa, R.; Fusco, R.; Gugliandolo, E.; Genovese, T.; Crupi, R.; Di Paola, R.; Cuzzocrea, S.; et al. Pea/polydatin: Anti-inflammatory and antioxidant approach to counteract DNBS-induced colitis. Antioxidants 2021, 10, 1–14, doi:10.3390/antiox10030464. IF: 6.312
 
86.   Siracusa, R.; Di Paola, R.; Cuzzocrea, S.; Impellizzeri, D.; et al. Fibromyalgia: Pathogenesis, Mechanisms, Diagnosis and Treatment Options Update. Int. J. Mol. Sci. 2021, 22, 3891, doi: 10.3390/ijms22083891. IF: 5.923
 
87.   Siracusa, R.; D’Amico, R.; Cordaro, M.; Peritore, A.F.; Genovese, T.; Gugliandolo, E.; Crupi, R.; Impellizzeri, D.; Cuzzocrea, S.; Fusco, R.; Di Paola, R.; et al. The Methyl Ester of 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid Reduces Endometrial Lesions Development by Modulating the NFkB and Nrf2 Pathways. Int. J. Mol. Sci. 2021, 22, 3991, doi: 10.3390/ijms22083991.  IF: 5.923
 
88.   Siracusa, R.; Schaufler, A.; Calabrese, V.; Fuller, P.M.; Otterbein, L.E. Carbon Monoxide: from Poison to Clinical Trials. Trends Pharmacol. Sci. 2021, doi:10.1016/j.tips.2021.02.003. IF: 14.819
 
89.   Cordaro M.*; Salinaro A.T.*; Siracusa R.*; D'amico R.; Impellizzeri D.; Scuto M.; Ontario M.L.; Interdonato L.; Crea R.; Fusco R.; Cuzzocrea S.; Di Paola R.; Calabrese V.; et al. Hidrox® and endometriosis: Biochemical evaluation of oxidative stress and pain. Antioxidants. 2021, 10(5), 720, doi: 10.3390/antiox10050720. IF: 6.312
 
90.   Fusco R.*; Salinaro A.T.*; Siracusa R.*, D'Amico R.; Impellizzeri D.; Scuto M.; Ontario M.L.; Crea R.; Cordaro M.; Cuzzocrea S.; Di Paola R.; Calabrese V.; et al. Hidrox ^® Counteracts Cyclophosphamide-Induced Male Infertility through NRF2 Pathways in a Mouse Model. Antioxidants. 2021, 10(5), 778, doi: 10.3390/antiox10050720. IF: 6.312
 
91.   Cordaro M.*; Trovato Salinaro A.*; Siracusa R.*; D'Amico R.; Impellizzeri D.; Scuto M.; Ontario M.L.; Crea R.; Cuzzocrea .; Di Paola R.; Fusco R.; Calabrese V.; et al. Hidrox ^® Roles in Neuroprotection: Biochemical Links between Traumatic Brain Injury and Alzheimer's Disease. Antioxidants. 2021, 10(5), 818, doi: 10.3390/antiox10050818. IF: 6.312
 
92.   Siracusa R.; D'Amico R.; Impellizzeri D.; Cordaro M.; Peritore A.F.; Gugliandolo E.; Crupi R.; Salinaro A.T.; Raffone E.; Genovese T.; Cuzzocrea S.; Fusco R.; Di Paola R.; et al. Autophagy and Mitophagy Promotion in a Rat Model of Endometriosis. Int. J. Mol. Sci. 2021, 22(10), 5074, doi: 10.3390/ijms22105074. IF: 5.923
 
93.   Peritore A.F.; D'Amico R.; Siracusa R.; Cordaro M.; Fusco R.; Gugliandolo E.; Genovese T.; Crupi R.; Di Paola R.; Cuzzocrea S.; Impellizzeri D.; et al. Management of Acute Lung Injury: Palmitoylethanolamide as a New Approach. Int. J. Mol. Sci. 2021, 22(11), 5533, doi: 10.3390/ijms22115533. IF: 5.923
 
94.   Genovese T.*; Siracusa R.*; D'amico R.; Cordaro M.; Peritore A.F.; Gugliandolo E.; Crupi R.; Salinaro A.T.; Raffone E.; Impellizzeri D.; Cuzzocrea S.; Fusco R.; et al. Regulation of inflammatory and proliferative pathways by fotemustine and dexamethasone in endometriosis. Int. J. Mol. Sci. 2021, 22(11), 5998, doi: 10.3390/ijms22115998. IF: 5.923
 
95.   D'amico R.; Salinaro A.T.; Fusco R.; Cordaro M.; Impellizzeri D.; Scuto M.; Ontario M.L.; Dico G.L.; Cuzzocrea S.; Di Paola R.; Siracusa R.*; Calabrese V.; et al. Hericium erinaceus and Coriolus versicolor modulate molecular and biochemical changes after traumatic brain injury. Antioxidants, 2021, 10(6), 898, doi: 10.3390/antiox10060898. IF: 6.312
 
96.   D'amico R.*; Fusco R.*; Siracusa R.*; Impellizzeri D.; Peritore A.F.; Gugliandolo E.; Interdonato L.; Sforza A.M.; Crupi R.; Cuzzocrea S.; Genovese T.; Cordaro M.; et al. Inhibition of p2x7 purinergic receptor ameliorates fibromyalgia syndrome by suppressing nlrp3 pathway. Int. J. Mol. Sci., 2021, 22(12), 6471, doi: 10.3390/ijms22126471. IF: 5.923
 
97.   D’amico R.*, Genovese T.*, Cordaro M.*, Siracusa R., Gugliandolo E., Peritore A.F., Interdonato L., Crupi R., Cuzzocrea S., Di Paola R., Fusco R., Impellizzeri D.; et al. Palmitoylethanolamide/Baicalein Regulates the Androgen Receptor Signaling and NF-κB/Nrf2 Pathways in Benign Prostatic Hyperplasia. Antioxidants 2021, 10(7), 1014; doi.org/10.3390/antiox10071014. IF: 6.312
 
98.   Siracusa R.*, Monaco F.*, D’amico R.*, Genovese T., Cordaro M., Interdonato L., Gugliandolo E., Peritore A.F., Crupi R., Cuzzocrea S., Impellizzeri D., Fusco R.; et al. Epigallocatechin-3-Gallate Modulates Postoperative Pain by Regulating Biochemical and Molecular Pathways. Int. J. Mol. Sci. 2021, 22(13), 6879; doi.org/10.3390/ijms22136879. IF: 5.923
 
99.   D’amico R., Trovato Salinaro A., Cordaro M., Fusco R., Impellizzeri D., Interdonato L., Scuto M., Ontario M.L., Crea R., Siracusa R.*, Cuzzocrea S., Di Paola R.; et al. Hidrox^® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain. Antioxidants 2021, 10(7), 1046; doi.org/10.3390/antiox10071046. IF: 6.312
 
100. Genovese T.*, Siracusa R.*, Fusco R.*, D’amico R., Impellizzeri D., Peritore A.F., Crupi R., Gugliandolo E., Morabito R., Cuzzocrea S., Salinaro A.T., Cordaro M.; et al. Atrazine inhalation causes neuroinflammation, apoptosis and accelerating brain aging. Int. J. Mol. Sci. 2021, 22(15), 7938; doi.org/10.3390/ijms22157938. IF: 5.923
 
101. Gugliandolo E., Macrì F., Fusco R., Siracusa R., D’amico R., Cordaro M., Peritore A.F., Impellizzeri D., Genovese T., Cuzzocrea S., Di Paola R., Licata P.; et al. The protective effect of snail secretion filtrate in an experimental model of excisional wounds in mice. Veterinary Sciences, 2021, 8(8), 167; 10.3390/vetsci8080167. IF: 2.304
 
102. Campolo M., Crupi R., Cordaro M., Cardali S.M., Ardizzone A., Casili G., Scuderi S.A., Siracusa R., Esposito E., Conti A., Cuzzocrea S.; et al. Co-ultra PEALut enhances endogenous repair response following moderate traumatic brain injury. Int. J. Mol. Sci., 2021, 22(16), 8717; doi.org/10.3390/ijms22168717. IF: 5.923
 
103. Gugliandolo E., Licata P., Peritore A.F., Siracusa R., D'amico R., Cordaro M., Fusco R., Impellizzeri D., Di Paola R., Cuzzocrea S., Crupi R., Interlandi C.D., et al. Effect of cannabidiol (Cbd) on canine inflammatory response: An ex vivo study on lps stimulated whole blood. Veterinary Sciences, 2021, 8(9), 185; doi: 10.3390/vetsci8090185. IF: 2.304
 
104. Di Paola. D, Iaria I., Capparucci F., Cordaro M., Crupi R., Siracusa R., D’Amico R., Fusco R., Impellizzeri D., Cuzzocrea S., Spanò N., Gugliandolo E., Peritore A.F., et al. Aflatoxin b1 toxicity in zebrafish larva (Danio rerio): Protective role of hericium erinaceus. Toxins, 2021, 13(10), 710; doi: 10.3390/toxins13100710. IF: 4.546
 
105. D'Amico R.*, Monaco F.*, Siracusa R.*, Cordaro M., Fusco R., Peritore A.F., Gugliandolo E., Crupi R., Cuzzocrea S., Di Paola R., Impellizzeri D., Genovese T., et al. Ultramicronized palmitoylethanolamide in the management of sepsis-induced coagulopathy and disseminated intravascular coagulation. Int. J. Mol. Sci., 2021, 22(21), 11388; doi: 10.3390/ijms222111388. IF: 5.923
 
106. Cordaro M.*, Salinaro A.T.*, Siracusa R.*, D'amico R., Impellizzeri D., Scuto M., Ontario M.L., Cuzzocrea S., Di Paola R., Fusco R., Calabrese V., et al. Key mechanisms and potential implications of hericium erinaceus in NLRP3 inflammasome activation by reactive oxygen species during alzheimer’s disease. Antioxidants, 2021, 10(11), 1664; doi:10.3390/antiox10111664. IF: 6.312
 
107. D'amico R.*, Cordaro M.*, Siracusa R.*, Impellizzeri D., Salinaro A.T., Scuto M., Ontario M.L., Crea R., Cuzzocrea S., Di Paola R., Fusco R., Calabrese V., et al. Wnt/β-catenin pathway in experimental model of fibromyalgia: Role of hidrox®. Biomedicines, 2021, 9(11), 1683; doi:10.3390/biomedicines9111683. IF: 6.081
 
108. Gugliandolo, E.; Cordaro, M.; Fusco, R.; Peritore, A.F.; Siracusa, R.; Genovese, T.; D’Amico, R.; Impellizzeri, D.; Di Paola, R.; Cuzzocrea, S.; et al. Protective effect of snail secretion filtrate against ethanol-induced gastric ulcer in mice. Sci. Rep. 2021, 11, doi:10.1038/s41598-021-83170-8. IF: 4.379
 
109. Di Paola D., Capparucci F., Lanteri G., Cordaro M., Crupi R., Siracusa R., D'amico R., Fusco R., Impellizzeri D., Cuzzocrea S., Spanò N., Gugliandolo E., Peritore A.F., et al. Combined toxicity of xenobiotics bisphenol a and heavy metals on zebrafish embryos (Danio rerio). Toxics, 2021, 9(12), 344; doi:10.3390/toxics9120344. IF: 4.546
 
110. Di Paola D., Natale S., Gugliandolo E., Cordaro M., Crupi R., Siracusa R., D’amico R., Fusco R., Impellizzeri D., Cuzzocrea S., Spanò N., Marino F., Peritore A.F., et al. Assessment of 2-Pentadecyl-2-oxazoline Role on Lipopolysaccharide-Induced Inflammation on Early Stage Development of Zebrafish (Danio rerio). Life, 2022, 12(1), 128; doi:10.3390/life12010128. IF: 3.817
 
111. Di Paola D., Natale S., Iaria C., Cordaro M., Crupi R., Siracusa R., D’amico R., Fusco R., Impellizzeri D., Cuzzocrea S., Spanò N., Gugliandolo E., Peritore A.F., et al. Intestinal Disorder in Zebrafish Larvae (Danio rerio): The Protective Action of N-Palmitoylethanolamide-oxazoline. Life, 2022, 12(1), 125; doi:10.3390/life12010125. IF: 3.817
 
112. Di Paola D., Capparucci F., Abbate J. M., Cordaro M., Crupi R., Siracusa R., D’Amico R., Fusco R., Genovese T., Impellizzeri D., Cuzzocrea S., Spanò N., Gugliandolo E. and Peritore A. F., et al. Environmental Risk Assessment of Oxaliplatin Exposure on Early Life Stages of Zebrafish (Danio rerio). Toxics, 2022, 10(2), 81; doi:10.3390/toxics10020081. IF: 4.546
 
113. Impellizzeri D.; Fusco R.; Genovese, Genovese T.; Cordaro M.; D’amico R.; Salinaro A.T.; Ontario M.L.; Modafferi S.; Cuzzocrea S.; Di Paola R.; Calabrese V.; Siracusa R., et al. Coriolus Versicolor Downregulates TLR4/NF-κB Signaling Cascade in Dinitrobenzenesulfonic Acid-Treated Mice: A Possible Mechanism for the Anti-Colitis Effect. Antioxidants, 2022, 11(2), 406; doi:10.3390/antiox11020406. IF: 6.312
 
114. Genovese T.; Duranti A.; D’amico R.; Fusco R.; Impellizzeri D.; Peritore A.F.; Crupi R.; Gugliandolo E.; Cuzzocrea S.; Di Paola R.; Siracusa R.*; Cordaro M., et al. Fatty Acid Amide Hydrolase (FAAH) Inhibition Plays a Key Role in Counteracting Acute Lung Injury. Int. J. Mol. Sci., 2022, 23(5), 2781; doi: 10.3390/ijms23052781. IF: 5.923
 
115. Gitto R., Vittorio S., Bucolo F., Pena-Diaz S., Siracusa R., Cuzzocrea S., Ventura S., Di Paola R., De Luca L., et al. Discovery of Neuroprotective Agents Based on a 5-(4-Pyridinyl)-1,2,4-triazole Scaffold. ACS Chemical Neuroscience, 2022, 13(5), pp. 581–586; doi: 10.1021/acschemneuro.1c00849. IF: 4.418
 
116. Ontario M.L., Siracusa R.*, Modafferi S., Scuto M., Sciuto S., Greco V., Bertuccio M.P., Trovato S. A., Crea R.; Calabrese E.J., Di Paola R., Calabrese, V., et al. Potential prevention and treatment of neurodegenerative disorders by olive polyphenols and hidrox. Mechanisms of Ageing and Development, 2022, 203, 111637; doi:10.1016/j.mad.2022.111637. IF: 5.432
 
117. D'amico R., Cordaro M., Fusco R., Peritore A.F., Genovese T., Gugliandolo E., Crupi R., Mandalari G., Caccamo D., Cuzzocrea S., Di Paola R., Siracusa R.*, Impellizzeri, D., et al. Consumption of Cashew (Anacardium occidentale L.) Nuts Counteracts Oxidative Stress and Tissue Inflammation in Mild Hyperhomocysteinemia in Rats. Nutrients, 2022, 14(7), 1474; doi: 10.3390/nu14071474. IF: 5.719
 
118. Genovese T., Impellizzeri D., D’amico R., Cordaro M., Peritore A.F., Crupi R., Gugliandolo E., Cuzzocrea S., Fusco R., Siracusa R.*, Di Paola R., et al. Resveratrol Inhibition of the WNT/β-Catenin Pathway following Discogenic Low Back Pain. Int. J. Mol. Sci., 2022, 23(8), 4092; doi: 10.3390/ijms23084092. IF: 5.923
 
119. Di Paola D., Iaria C., Lanteri G., Cordaro M., Crupi R., Siracusa R., D'amico R., Fusco R., Impellizzeri D., Cuzzocrea S., Spanò N., Gugliandolo E., Peritore A.F., et al. Sensitivity of Zebrafish Embryogenesis to Risk of Fotemustine Exposure. Fishes, 2022, 7(2), 67; doi: 10.3390/fishes7020067. IF: 2.385
 
120. Genovese T., Impellizzeri D., D’amico R., Fusco R., Peritore A.F., Di Paola D., Interdonato L., Gugliandolo E., Crupi R., Di Paola R., Cuzzocrea S., Cordaro, M., Siracusa R., et al. Role of Bevacizumab on Vascular Endothelial Growth Factor in Apolipoprotein E Deficient Mice after Traumatic Brain Injury. Int. J. Mol. Sci., 2022, 23(8), 4162; doi: 10.3390/ijms23084162. IF: 5.923
 
121. Di Paola R.*, Modafferi S.*, Siracusa R., Cordaro M., D'amico R., Ontario M.L., Interdonato L., Salinaro A.T., Fusco R., Impellizzeri D., Calabrese V., Cuzzocrea, S., et al. S-Acetyl-Glutathione Attenuates Carbon Tetrachloride-Induced Liver Injury by Modulating Oxidative Imbalance and Inflammation. Int. J. Mol. Sci., 2022, 23(8), 4429; doi: 10.3390/ijms23084429. IF: 5.923
 
122. D'amico R., Gugliandolo E., Cordaro M., Fusco R., Genovese T., Peritore A.F., Crupi R., Interdonato L., Di Paola D., Cuzzocrea S., Impellizzeri D., Siracusa R.*, Di Paola R., et al. Toxic Effects of Endocrine Disruptor Exposure on Collagen-Induced Arthritis. Biomolecules, 2022, 12(4), 564; doi: 10.3390/biom12040564. IF: 4.879
 
123. Genovese T.; Cordaro M.; Siracusa R.; Impellizzeri D.; Caudullo S.; Raffone E.; Macrì F.; Interdonato L.; Gugliandolo E.; Interlandi C.; Crupi R.; D'Amico R.; Fusco R.; Cuzzocrea S.; Di Paola R. et al. Molecular and Biochemical Mechanism of Cannabidiol in the Management of the Inflammatory and Oxidative Processes Associated with Endometriosis. Int. J. Mol. Sci., 2022, 23(10), 5427; doi: 10.3390/ijms23105427. IF: 5.923
 

CONGRESS 
Poster: 
 
1. Neuroprotection by association of palmitoylethanolamide with luteolin in experimental Alzheimer’s diseasemodels:  the control of neuroinflammation
Siracusa R, Paterniti I, Cordaro M, Campolo M, Cornelius C, Navarra M, Cuzzocrea S, Esposito E
Convegno monotematico SIF = Farmacognosia: nuove opportunità terapeutiche dal mondo vegetale. Napoli, 20-21Giugno 2014
 
2. Liver X receptors activation, through TO901317 binding, decreases neuroinflammation in Parkinson’s disease
Rosalba Siracusa, Michela Campolo, Irene Paterniti, Marika Cordaro, Rosanna Di Paola, Carolin Cornelius, MicheleNavarra, Salvatore Cuzzocrea and Emanuela Esposito.
9th FENS Forum of Neuroscience. Milano 5-9 Luglio 2014
 
3.  Resveratrol  and  Mangiferin  protects  lung  from  oxidative  stress  in  bleomycin- treated mice
R. Siracusa, I. Paterniti, M. Cordaro, D. Impellizzeri, R. Crupi, G. Bruschetta, E. Esposito and S. Cuzzocrea SeminarioNazionale in Farmacologia e Scienze Affini per Dottorandi, Assegnisti di Ricerca, Postdottorandi e Specializzandi.Rimini 16-18 Settembre 2014
 
4. B Cell-Targeted Therapy with Anti-CD20 Monoclonal Antibody Reduced Secondary Tissue  Damage  andEnhanced Behavioral Recovery Following  Experimental  Spinal Cord Injury in Mice
R. Siracusa, D. Impellizzeri, M. Cordaro, R. Crupi, E. Esposito and S. Cuzzocrea
37° Congresso della Società Italiana di Farmacologia. Napoli 27-30 Ottobre 2015
 
5. KU0063794, a dual mTORC1 and mTORC2 inhibitor, reduces neural tissue damage and locomotorimpairment after spinal cord injury in mice
Rosalba Siracusa, Marika Cordaro, Irene Paterniti, Daniela Impellizzeri, Emanuela Esposito, and Salvatore Cuzzocrea
1st  Challenges in inflammation meeting: “Regulatory checkpoints and resolution”. Firenze
Marzo 30 2016 - Aprile 01 2016
 
6.  Micronized  palmitoylethanolamide  (PEA-m):  a  new  pharmacological  strategy  to preventneurodegenerative diseases associated to the old age
Rosalba Siracusa, Daniela Impellizzeri, Marika Cordaro, Giovanna Casili, Rosalia Crupi, Emanuela Esposito andSalvatore Cuzzocrea
“Controversies in Neurodegeneration” Coro di Notte Monastero dei Benedettini, P.zza Dante
Catania 9-10 Giugno 2016
 
6. Effects of 2-Pentadecyl-2-oxazoline (PEA-OXA), the oxazoline of PEA, in an experimental model of carrageenan-induced hindpaw inflammation: involvement of PPAR-α?
R. Siracusa, D. Impellizzeri, R. Crupi, M. Cordaro, E. Esposito, S. Cuzzocrea
XIX SIF Seminar on Pharmacology for PhD Students, Fellows, Post Doc and Specialist
Trainees. Rimini 20-22 Settembre 2016
 
7. Anti-inflammatory and neuroprotective effects of co-ultraPEALut in a mouse model of vascular dementia
Rosalba Siracusa, Daniela Impellizzeri, Marika Cordaro, Rosalia Crupi, Emanuela Esposito, Stefania Petrosino,Salvatore Cuzzocrea
13th World Congress on Inflammation. Londra 8-12 Luglio 2017
 
8. Anti-inflammatory and neuroprotective effects of co-ultraPEALut in a mouse model of vascular dementia
R. Siracusa, D. Impellizzeri, M. Cordaro, R. Crupi, E. Esposito, S. Cuzzocrea
38° Congresso Nazionale: Farmaci, Salute, e Qualità della Vita. Rimini 25-28 Ottobre 2017
 
9. Co-ultraPEALut: role in preclinical delirium manifestations
Rosalba Siracusa, Rosalia Crupi, Marika Cordaro, Daniela Impellizzeri, Rosanna Di Paola and Salvatore Cuzzocrea
XXI SIF Seminar on Pharmacology for PhD Students, Fellows, Post Doc and Specialist
Trainees. Bresso 19-22 Settembre 2018
 
10.  Effects of  a  new compound containing Palmitoylethanolamide  and Baicalein  in
Myocardial Ischaemia/Reperfusion Injury in VIVO
Siracusa R., D’amico R., Fusco R., Gugliandolo E., Cordaro M., Impellizzeri D., Peritore A. F., Crupi R., Cuzzocrea S.and Di Paola R.
Convegno  Monotemaco  SIF -  Cardiovascular  diseases:  from  popula,on  to  basic  science searching for newtherapeu,c targets. Napoli 26-27 Settembre 2018
 
11.  The  role  of  FPR1  receptor  and  their  relationship  to  neuroinflammation  and neurodegeneration intraumatic brain injury
R. Siracusa, S. Cuzzocrea, E. Gugliandolo, R. Fusco, R. Di Paola
Neuroscience 2018. San Diego 3-7 Novembre 2018
 
12. The protective effects of micronized PEA (PEA-m) formulation on postoperative pain in rats
Siracusa R., Fusco R., Impellizzeri D., Peritore A. F., Cordaro M., D’Amico R., Gugliandolo
E.1, Crupi R., Cuzzocrea S. and Di Paola R.
1st   International  Conference  on  Neuroprotection  by  Drugs,  Nutraceuticals  and  Physical
Activity. Rimini 6-7 Giugno 2019
 
13. The protective effects of micronized PEA (PEA-m) formulation on postoperative pain in rats
Siracusa R., Fusco R., Impellizzeri D., Peritore A. F., Cordaro M., D’Amico R., Gugliandolo
E.1, Crupi R., Cuzzocrea S. and Di Paola R.
14th World Congress on Inflammation. Sydney 15-19 Settembre 2019
 
14.  Anti-Inflammatory  and  Anti-Oxidant  Activity  of  Hidrox®   in  Rotenone-Induced
Parkinson’s Disease in Mice
Rosalba  Siracusa, Maria  Scuto,  Roberta  Fusco,  Angela  Trovato,  Maria  Laura  Ontario, Roberto Crea, Rosanna DiPaola, Salvatore Cuzzocrea and Vittorio Calabrese
52° Congresso Nazionale SiBioC – Medicina di Laboratorio. Virtual 6-8 Ottobre 2020
 
15. Molecular and biochemical changes occurring in the brain after traumatic brain injury and leading to Parkinson's disease: modulation by Hericium erinaceus and Coriolus versicolor. 
Rosalba Siracusa, Maria Laura Ontario, Roberta Fusco, Daniela Impellizzeri, Maria Scuto, Angela Trovato, Rosanna Di Paola, Vittorio Calabrese and Salvatore Cuzzocrea
45° Virtual FEBS Congress, Virtual 3-8 Luglio 2021 Slovenia
 
16. Hidrox® roles in neuroprotection: biochemical links between traumatic brain injury and Alzheimer’s disease        
Rosalba Siracusa, Marika Cordaro, Roberta Fusco, Ramona D’Amico, Daniela Impellizzeri, Salvatore Cuzzocrea, Rosanna Di Paola
FENS, Virtual 25-26 Agosto 2021
 
17. Hidrox® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain
Rosalba Siracusa, Ramona D'Amico, Rosanna Di Paola
53rd National Congress SIBioC 2021. Laboratory Medicine in Proximity Medicine: telemedicine, roles and skills, Virtual Edition 11-13 October 2021
 
 
Oral presentation:
 
1. 1. Anti-Inflammatory and Anti-Oxidant Activity of Hidrox® in Rotenone-Induced Parkinson's Disease in Mice
Rosalba Siracusa, Roberta Fusco, Angela Found, Roberto Crea, Rosanna Di Paola, Salvatore Cuzzocrea and Vittorio Calabrese
Food Science and Nutrition. Virtual 2-3 November 2020
 
2. Anti-Inflammatory and Anti-Oxidant Activity of Hidrox® in Rotenone-Induced Parkinson's Disease in Mice
Rosalba Siracusa, Roberta Fusco, Angela Found, Roberto Crea, Rosanna Di Paola, Salvatore Cuzzocrea and Vittorio Calabrese
40th SIF Congress, Virtual 9-13 March 2021
 
3. Molecular and biochemical changes occurring in the brain after traumatic brain injury and leading to Parkinson's disease: modulation by Hericium erinaceus and Coriolus versicolor
Rosalba Siracusa, Ramona D'Amico, Roberta Fusco, Marika Cordaro, Daniela Impellizzeri, Salvatore Cuzzocrea, Rosanna Di Paola
Nutrition & Nursing, Webinar 12-13 June 2021
 
4. Hidrox® roles in neuroprotection: biochemical links between traumatic brain injury and Alzheimer's disease
Rosalba Siracusa, Roberta Fusco and Rosanna Di Paola
61st SIB 2021 Congress, Virtual Edition 23-24 September 2021
 
5. Seril-18, a new synthetic molecule, inhibits α-synuclein aggregation in an experimental model of Parkinson's disease.
Rosalba Siracusa, Marika Cordaro, Ramona D'Amico, Roberta Fusco, Daniela Impellizzeri, Rosanna Di Paola, Salvatore Cuzzocrea
13th ÖGMBT Annual Meeting: From molecular machines to translational medicine, Virtual Edition from 20 September to 14 October 2021
 
6. Hidrox® and Chronic Cystitis: Biochemical Evaluation of Inflammation, Oxidative Stress, and Pain
Rosalba Siracusa, Ramona D'Amico, Angela Trovaro Salinaro, Marika Cordaro, Roberta Fusco, Daniela Impellizzeri, Livia Interdonato, Maria Scuto, Maria Laura Ontario, Roberto Crea, Vittorio Calabrese, Rosanna Di Paola and Salvatore Cuzzocrea
1st Meeting of the SIF Immunopharmacology WG - RECENT DEVELOPMENTS IN IMMUNOPHARMACOLOGY. Perugia 24-26 November 2021
 
7. Hidrox® and Endometriosis: Biochemical Evaluation of Oxidative Stress and Pain
Rosalba Siracusa, Marika Cordaro, Ramona D'Amico, Daniela Impellizzeri, Roberta Fusco, Vittorio Calabrese, Salvatore Cuzzocrea, Rosanna Di Paola
4th Online International Conference on Nutrition and Nutraceuticals. Virtual 29-30 November 2021
 
8. Hidrox® roles in neuroprotection: biochemical links between traumatic brain injury and Alzheimer's disease
Rosalba Siracusa, Marika Cordaro, Roberta Fusco, Ramona D'Amico, Daniela Impellizzeri, Salvatore Cuzzocrea, Rosanna Di Paola
Neuroscience and Brain Disorders, Virtual 2-4 December 2021
 
9. Key mechanisms and potential implications of Hericium erinaceus in NLRP3 inflammasome activation by reactive oxygen species during Alzheimer's Disease
Rosalba Siracusa, Marika Cordaro, Roberta Fusco, Daniela Impellizzeri, Ramona D'Amico, Salvatore Cuzzocrea, Vittorio Calabrese, Rosanna Di Paola
2nd International Conference on Neuroprotection by Drugs, Nutraceuticals and Physical Activity. Virtual 9-10 December 2021
 
10. Wnt / β-catenin pathway in fibromyalgia: role of Hidrox
Rosalba Siracusa, Ramona D'Amico, Marika Cordaro, Roberta Fusco, Daniela Impellizzeri, Salvatore Cuzzocrea, Rosanna Di Paola
Webinar on Nutritional Health and Food Science. Virtual 3-4 February 2022
  
 
OTHER SKILL
 
1. TRAINING AND UPDATE CONCERNING THE EMPLOYMENT OF ANIMALS FOR SCIENTIFIC AND EDUCATIONAL PURPOSE. Caltanissetta 15-18 May 2018
 
1. ECDL – European Computer Driving License